The Role of Thymic Stromal Lymphopoietin

Thymic Stromal Lymphopoietin Amplifies

Cell Responses in the Respiratory Mucosa Stromal Lymphopoietin on Antiviral CD8 T A Direct and Nonredundant Role for Thymic

Thymic stromal lymphopoietin promotes human eosinophil-basophil lineage commitment: a key role for tumor necrosis factor-alpha

Background Allergic diseases are characterized by tissue eosinophilic and basophilic inflammation. Both epithelial-derived thymic stromal lymphopoietin (TSLP) and eosinophil/ basophil (Eo/B) lineage-committed progenitor cells are upregulated and found at sites of allergic inflammation [1-3]. We have previously shown that TSLP mediates the differentiation of peripheral blood (PB) CD34 progenitor...

Thymic Stromal Lymphopoietin Interferes

Thymic stromal lymphopoietin: master switch for allergic inflammation

Thymic stromal lymphopoietin (TSLP) is an interleukin (IL) 7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses. TSLP is highly expressed by keratinocytes in skin lesions of patients with atopic dermatitis and is associated with dendritic cell activation in situ, suggesting that TSLP might be a master switch for allergic inflammation at the epithelial cell...